tag:blogger.com,1999:blog-9158169732362839786.post6212115333182399762..comments2024-03-13T00:23:20.750-07:00Comments on Area-1255: Natural Herbal Histamine 3 H(3)R Antagonists.Jason Malek Russohttp://www.blogger.com/profile/13484819788942297056noreply@blogger.comBlogger10125tag:blogger.com,1999:blog-9158169732362839786.post-20595249539524534382018-12-26T23:28:53.574-08:002018-12-26T23:28:53.574-08:00Very interesting post, Thank you.
regarding the &#...Very interesting post, Thank you.<br />regarding the 'mind clarity' effect you report when using h3r antagonists<br />Do you have some dosing information with yamoa, kutaj vs pitolisant?Liron mulahttps://www.blogger.com/profile/13852132580874198401noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-27132907846058395812018-03-30T14:44:26.841-07:002018-03-30T14:44:26.841-07:00I mean that Conessine is, IN ADDITION to a Histami...I mean that Conessine is, IN ADDITION to a Histamine H3-antagonist/receptor blocker, an A2-antagonist and D2S-antagonist. :-)Jason Malek Russohttps://www.blogger.com/profile/13484819788942297056noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-886455822441101902018-03-30T14:43:46.911-07:002018-03-30T14:43:46.911-07:00Conessine is an alpha-2-adrenergic antagonist so i...Conessine is an alpha-2-adrenergic antagonist so it raises Noradrenaline, Acetylcholine, Histamine etc through that pathway as well.<br />It also mildly blocks Dopamine-autoreceptors, eliciting "extra" dopamine release.<br />--> https://www.ncbi.nlm.nih.gov/pubmed/18683917Jason Malek Russohttps://www.blogger.com/profile/13484819788942297056noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-77809729322894305322018-03-29T15:16:22.428-07:002018-03-29T15:16:22.428-07:00Awesome man. Yeah, I reckon Magnolia will do the t...Awesome man. Yeah, I reckon Magnolia will do the trick for me. Well it proved to work last time. Today I've upped the dosage on Conessine. You should mention that Conessine displays strong binding to adrenergic receptors... What would this elicit? How would this shape the subjective experience?<br /><br />Cheers. Lokzohttps://www.blogger.com/profile/09150091347819869004noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-74006575091382405542018-03-24T04:31:58.352-07:002018-03-24T04:31:58.352-07:00Cyproheptadine or other antihistamines should do t...Cyproheptadine or other antihistamines should do the trick. Magnolia maybe a little. Aswagandha + L-Theanine is what I used to go to sleep on high-dose Conessine.Jason Malek Russohttps://www.blogger.com/profile/13484819788942297056noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-63465227771265541642018-03-24T04:31:32.690-07:002018-03-24T04:31:32.690-07:00This comment has been removed by the author.Jason Malek Russohttps://www.blogger.com/profile/13484819788942297056noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-6617330465780930252018-03-23T18:11:43.889-07:002018-03-23T18:11:43.889-07:00Found a way to remedy the insomnia that it can cau...Found a way to remedy the insomnia that it can cause? Any antagonistic herbs/neutraceuticals to offset this? The obvious ones are anti-histamines, but what about say GABA, magnesium, or Magnolia? Anonymoushttps://www.blogger.com/profile/01317384849603436954noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-71824540922577140252016-09-02T04:38:08.850-07:002016-09-02T04:38:08.850-07:00Hello,
I read your post on longecity about H3-anta...Hello,<br />I read your post on longecity about H3-antagonist. Found the part with kutaj increasing strength due to calcium channel enhancement very interresting as I am competing. Coul you please guide me to some studies, etc regarding this aspect (kutaj, calcium channel enhancement, etc).<br />TY much!Christianhttps://www.blogger.com/profile/07694953689028847594noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-6558694892920731252014-08-24T20:56:50.939-07:002014-08-24T20:56:50.939-07:00Yeah, I did quite a bit of research on it myself. ...Yeah, I did quite a bit of research on it myself. Thioperamide is supposed to be the strongest out of all of them. Good luck getting your hands on it though! ;)Corageonhttps://www.blogger.com/profile/17462310938066502238noreply@blogger.comtag:blogger.com,1999:blog-9158169732362839786.post-2895006278433747342014-08-24T10:31:58.899-07:002014-08-24T10:31:58.899-07:00The concept of H3R antagonism is pretty new, and v...The concept of H3R antagonism is pretty new, and very interesting. If I recall correctly, they were studying Pitolisant for the treatment of Alzheimer's, Dementia and neuroprotection. Same with Thioperamide which happens to be in-dev anti-inflammatory / anti-itching and has protective effects on scopolamine induced memory impairment, as well as providing anti-seizure and anti-depressant effects. The effects on the classic "immobility time" test were quite impressive. I'll have to dig it up, but I'm sure if anyone - you already know about it Jay. You have been studying this a lot longer than I have.Anonymousnoreply@blogger.com