Symptoms/Signs of High And Low Endorphin Levels (Including Psychological Manifestations) (Symptoms of High/Low Brain Opioid Activity)

Area-1255 : is here again with another 'outside the box' article. This time we will be exploring the differences between high and low endorphin symptomology ; this will give us a sort of 'routine' to deliberate on before making any particular medical decisions and / or consultations.


*MANY* (but not all) endocrine disorders (hormone disorders) stem from dysfunctional opioid systems (1) in the Brain, Spinal Cord and Peripheral Nervous System (2). This includes receptor downregulation and / or supersensitivity (3). 


This is demonstrated, not just in opioid dependent individuals but Also those with congenital (from birth) opioid-receptor mutations/polymorphisms (4) (5) (6) (7).

Here we will go over the acute and long-term effects of physiological opioid-function abnormalties and endorphin imbalance/s.

The SYMPTOMS of Very HIGH β-Endorphin and / or DYNORPHIN levels (includes naturally or genetically) are...

• Social Isolation, and low social motivation (8) (9)
• Impulsivity (due to excess Kappa/k-opioid activation, dynorphin mediated) (10) (11) (12)
• Depression or Anhedonia (Emotional Numbness) (13) (14)
• Low/Absent Sex Drive (15) (16) (17) (18)
• Low Testosterone / Universal Hypogonadism in either Sex (19) (20) (21) (22) (23) (24)
• Infertility : in both Men and Women ; Low Sperm Count, Lack of ovulation (25) (26) (27) :-: (28) (29) (30)
• COGNITIVE INFLEXIBILITY (unable to switch Tasks easily and unable to understand or unwillingness to Internalize what one is not used to; unable to pick up new 'concepts' and generally resorts to what one knows) (31) (32) (33) (34) (35)
• Indifference, lack of competitive behavior, doesn't care about 'Winning' or 'Losing' (36) (37).
• EXTREME FATIGUE / LETHARGY (38) (39) (40) (41)
• Lack of the Ability to ''Cry''. (42) (43) (44)
• Constipation (45) (46)

To correct most of those issues you must.

• Resolve the underlying hormonal imbalance (too much Progesterone or Estrogen etc)
• Use Naltrexone in the short-term if no anxiety disorder is present. (25-50 mg once per day)
• Use Cialis to counter-act the sexual deficits in the short-term. (5-20 mg once per day)

TO Permanently SOLVE Opioid IMPOTENCE & Sexual Deficit as well as REVERSING/CORRECTING NATURALLY HIGH OPIOID-ENDORPHIN AXIS LEVELS, simply Click the ~Image~ below.

The SYMPTOMS of Very LOW β-Endorphin and / or DYNORPHIN levels (includes naturally or genetically) are...

• Anxiety; especially anticipatory Anxiety (47) (48)
• Residual Ruminations (feelings of excess/persistent dread or tremor after traumatic/stress event/s) (49)
• Risk-Taking Behavior (living ''on edge'') (50) (51)
• Loves working Out; sometimes to the Point of 'over-training'. (52)
• Workaholicism and Fast, Intuitive, Bright and Dedicated mind, but with underlying internal anxiety and persistent emotional fastening/Reservations. (53) (54) 
• Depressive, even Suicidal tendencies in *some* individuals Affected. (depends on other factors; such as psychosocial status , income, past experiences and personality traits as well as belief system influence/s) (55)
• Rigorous 'testing' or even compulsive behavior; constant checking; O.C.D (!)

**It is important to note that both high and low beta-endorphin levels can lead to obsessive-compulsive disorder**.