Wellbutrin Effect on Testosterone in Humans (Bupropion Effect on Testosterone)

Wellbutrin/Bupropion is a dopaminergic-noradrenergic antidepressant introduced and first patented by Burroughs Wellcome [1] and then followed through and marketed by GlaxoSmithKline [2]. Since its long stay on the market of Psychiatric medications - it has undergone much study and has found additional uses including smoking cessation [3] and Seasonal Affective Disorder [4] [5](winter depression). 

What many people want to know though, is what kind of effect does Wellbutrin have on sex hormones; namely Testosterone?

• Wellbutrin decreases Prolactin in Men & Women, though to a lesser extent than in rats [6].
• Wellbutrin increases DHEA-S levels [7].
• Wellbutrin mildly increased Testosterone in some men [8]. 
• Wellbutrin had some effects on cytokines [9].
• Wellbutrin increased gonadotropins in 1 study out of 11 [10].

CONCLUSION: Wellbutrin (Bupropion) does not have enough evidence to say it is a ''testosterone-booster'' but it certainly doesn't have negative effects on hormones.

In/Tags: bupropion effect on testosterone, bupropion effect on testosterone in humans, wellbutrin effect on testosterone, wellbutrin testosterone humans, wellbutrin effect on testosterone in humans,