Kratom Mechanism of Action 2019 (What is Kratom's Mechanism of Action 2019) What is Kratoms Mechanism of ACTION 2019

To enhance Kratom's effects; we need to understand its mechanisms of action.

It activates the following painkilling receptors...

1. Mu or U opioid-receptor; similar to Morphine & Heroin [7].
2. It activates the K-opioid receptor [8] and delta-receptors [9] - both painkilling receptors [10].
3. It activates Alpha-2-Receptors [11]. Thus, decreasing Adrenaline - and decreasing Anxiety levels [12].
4. It activates dopamine activity [13] creating pleasant & euphoric effects [14] [15] [16].
5. It activates serotonin 5-HT2A receptors [17]; creating mild dissociative effects [18] [19] [20].

To prolong the effects of Kratom - there are a few strategies we can use!

1. We can combine an MAO-B inhibitor [↑ dopamine] like Dopa-Mind (Life Extension) [21]. This prolongs Kratom's effects dramatically [22]. This research paper elaborates more on this effect - and its mechanisms.
2. We can eat Dark Chocolate or supplement high-potency cocoa extract - which increases endorphins [beta-endorphin] [23].
3. Syrian Rue [24]: Syrian Rue is able to amplify Kratom's effects by providing additional euphoria/mood-lift and energizing the body's Spiritual Zones.
4. We can add things like Maca - to potentiate Cannabinoid-activity [25] - Maca also blocks the breakdown of endorphins & enkephalins; increasing the effects of Kratom and opioids.
5. Cannibidiol (CBD Oil) [26] [27]: It increases beta-endorphin as well and increases Happiness and easy-goingness. 
6. Turmeric (Curcumin) [28]: Turmeric blocks endorphins "feel good chemicals" from being broken down and it allows you digest/absorb Kratom better [29].

OTHER ARTICLE: Potentiating Kratom Naturally and With Drugs [2019]

WARNING: Never combine Kratom with strong sedatives; especially Meds/Drugs like Seroquel (quetiapine) [30].

NOTE: This entire post was written on the basis of True Science - and I also coordinated with others (cousin is a Medical Doctor) - he helped me put this together and found some locked-away VIP articles.

...There are hidden secrets about Kratom [2019].
I wrote a Book about a novel strain of Kratom not yet available on the market.

 

*This secret strain of Kratom is currently being studied by Russian Scientists as it has the unusual quality of regenerating MU-opioid receptors causing a 150% increase in receptors for it and other opiates/opioids to bind to.

One last strategy to enhance Kratom's effects is to supplement with Egyptian Blue Lotus (Nelumbo Nucifera). 

Blue Lotus Extracts [31]; it is an herb that contains the Dopamine-agonist compound Apomorphine [32] as well as other chemicals that support dopamine-release [33] [34] - it affects opioid-receptors and maximizes them [35]. This allows it to make Kratom more effective [36] [37] [38].

Blue Lotus has an important history by Ancient Egyptians and was the Pharaoh's prized plant remedy and used frequently to boost his Energy Level & Charisma. It also is rumored to be the reason why the Egyptian Royalty - lived longer and maintained greater connections to "The Dragon" [leviathan].

...That is the 'Serpent' emblem on the Pharaoh's Crown [link].

It (blue lotus) is unique and has rare chemicals that NO other herb has or contains [39].

***SOURCES/REFERENCES***

KRATOM AND THE OPIOID CRISIS
Innov Clin Neurosci. 2018 Jun 1; 15(5-6): 11.
Published online May-Jun 2018.
PMID: 30013812

Endorphinergic modulation of neural reward systems indicated by behavioral changes.
Pharmacol Biochem Behav. 1984 Aug;21(2):259-66.

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