Guide to Using L-Lysine Appropriately (For Immune Support, Anxiety, IBS, Heart Health)

GUIDE TO L-LYSINE SUPPLEMENTATION (with Study Citations at Each)

L-Lysine is an essential amino acid that many of us do not get enough of in our diet, and given that our bodies can not produce it, it is absolutely crucial we get in our diet, at least, for ideal health.

• Lysine fortification has been shown to improve / reduce Anxiety in those living in impoverished regions, including 'third-world' countries and places like Syria, where grain-based diets predominate [1]. 
• Lysine improves immune health at 1-2 grams per day , that's 1000 miligrams (mg) to 2000 miligrams [2] [3] [4].
• Lysine can be used to treat diarrhea predominant IBS [5], and for this purpose, should be ideally used at a minimum of 3 grams per day |3000 mg|...[6] [7].
• L-Lysine can be used for Anxiety, and for this purpose 4000 mg which is 4 grams can be used at once, if you go beyond this amount, Arginine supplementation should be considered mandatory in proportion to the Lysine dose [8] [9] [10].
• To reduce arterial calcification and to thin the blood, Lysine should be used with Vitamin C, 1.5  grams that's 1,500 miligrams -mg- of Lysine and about 2 grams or 2000 mg of Vitamin C per day [11] [12] [13].... This amount (1.5 grams, 1500mg) of Lysine or up to 3000 mg can also alleviate/eliminate angina (chest pain) [14].. Again, it should be used with Vitamin C for this purpose as well.
• L-Lysine has been studied as an adjunct for Schizophrenia, and for this purpose, you want to use 6 grams of Lysine, 6000 mg a day [15].
• To increase calcium absorption and bone health, 800 mg - 2000 mg / day can be used, L-Lysine is very efficient at increasing calcium absorption and delivery, while removing calcium from organs where it should not accumulate (heart etc), however, it can increase the amount into myocytes if necessary [16] [17] [18].
• For PREVENTION of Alzheimer's / Dementia , Lysine should be used at 1.5 grams or 1,500 mg or MORE/per day [19].
• For reduction of Cortisol, use 3 grams of Lysine and 3 grams of Arginine, that's 3000 mg of L-Lysine and 3000 mg of L-Arginine, once per day, preferably at night [20].

HOW TO DOSE L-LYSINE (with food, empty stomach etc)

• For general immunity, or herpes infections, 1-1.5 grams or three 500 mg capsules per day with food or a morning or afternoon meal will be sufficient.
• For Gut/IBS Issues, or for Anxiety / Mental Issues, it should be taken on an empty stomach at 3-5 grams or 3000 - 5000 mg one time per day, preferably mid to late afternoon or even evening time.
• For HEART health, including blood thinning, L-Lysine at 1,500 mg or even 2,000 mg so 1.5 grams or 2 grams With Vitamin C at 2 grams or 2000 mg once per day. Try eating oats every day or at least 3 times per week, preferably 4 - 5 days minimum though.

**OTHER CITATIONS / SOURCES**
Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans.

Lysine fortification reduces anxiety and lessens stress in family members in economically weak communities in Northwest Syria

Effect of lysine supplementation on health and morbidity in subjects belonging to poor peri-urban households in Accra, Ghana

l-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats

Two essential amino acids, L-lysine and L-histidine, in five types of experimental seizures.


My recommended L-Lysine supplements are below.

1. The first is powder, can be dissolved in a drink.
2. The second is capsules, easily digestable.
3. The third is not Lysine, it is my recommended Vitamin-C Product.