Experiences with Pitolisant (What does Pitolisant "Feel" Like?) (What do H3 Antagonists Feel Like)

We've now written multiple articles regarding brain histamine :

• Histamine Receptors H1,H2,H3 and Neurotransmitter / Hormone Release
• How to Tell if you are Low Histamine or High Histamine 
• Low Histamine Levels ; A disturbing Phenomenon leading to Fatigue, Paranoia, Anxiety & Scattered Thoughts.
• The Key's to Re-Activating the Hypothalamus / Pituitary may be the Same as Those in Treating Narcolepsy
• The Hyperbolic Histamine Stack (Extreme Histamine-Boosting Stack)

With all of this information, and with anecdotal experiences, one can conclude that histamine, and in particular, Histamine H3-receptors are of vital importance in alertness/awakeness, Cognition and Memory. But that's  not enough for most people - people want to know what higher brain histamine and H3-antagonists ''feel like''. That's fine by me.

MY EXPERIENCE WITH PITOLISANT & KUTAJ Bark (Containing Conessine)

1. To be honest, the most noticeable effects of both of these are a near immediate increase in sensory awareness, that is - lights are brighter, details are more easily noticeable, speed of thinking is up and senses such as smell and taste are up. 
2. In addition to that though, there is a clear increase in the ability to ''bridge thoughts'' and to draw connections in complex problems (such as in mathematics, visual solutions and finding alternative ways to get places). Now, we all have a natural instinct (generally) to find alternatives when one road is blocked off, but these H3-antagonists facilitate that function, IMHO.
3. Clear-headed thinking is important, and H3-antagonists (boosting histamine) seem to allow for clarity that in my opinion, is unsurpassed.
4. Intellectual and analytical thinking are increased a bit by means of increased ''idea flow'' and creativity, which in my opinion is BECAUSE the H3-antagonists increase thought speed and awareness, thus taking in details more readily and processing them better.
5. There is a slight euphoria that can be unlocked with H3-antagonists, and this euphoria comes mainly as increased emphasis on all things - such as symbolic speech/writing, and fascination with magical meanings - of which could clearly be attributed to increased catecholamine release caused by histamine activation of H1R's and H2R's. It is important to remember though, that histamine is not typically a euphoric substance in small amounts, it requires the blocking of H3R's to allow for histamine to pass that threshold, and for some people, that may not even be enough - but rather that supplementing with things like L-Histidine + Forskolin may be the only way to unlock histamine's euphoric potential.

*****Additional Notes : I've also found that using a few puffs of an inhaler up the nose (literally) or any other beta-adrenergic agonist (such as Higenamine) remarkably enhances the effects of H3-antagonists. 

My favorite H3-antagonist is listed below, for your convenience.

Click here if the image isn't working; it leads to Amazon, on their seller page.

                                             

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