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Showing posts with label kratom mechanism of action 2019. Show all posts
Showing posts with label kratom mechanism of action 2019. Show all posts

Friday, August 2, 2019

Kratom Mechanism of Action 2019 (What is Kratom's Mechanism of Action 2019) What is Kratoms Mechanism of ACTION 2019

To enhance Kratom's effects; we need to understand its mechanisms of action.

It activates the following painkilling receptors...

  1. Mu or U opioid-receptorsimilar to Morphine & Heroin [7].
  2. It activates the K-opioid receptor [8] and delta-receptors [9] - both painkilling receptors [10].
  3. It activates Alpha-2-Receptors [11]. Thus, decreasing Adrenaline - and decreasing Anxiety levels [12].
  4. It activates dopamine activity [13] creating pleasant & euphoric effects [14] [15] [16].
  5. It activates serotonin 5-HT2A receptors [17]; creating mild dissociative effects [18] [19] [20].
To prolong the effects of Kratom - there are a few strategies we can use!

  1. We can combine an MAO-B inhibitor [ dopamine] like Dopa-Mind (Life Extension) [21]. This prolongs Kratom's effects dramatically [22]. This research paper elaborates more on this effect - and its mechanisms.
  2. We can eat Dark Chocolate or supplement high-potency cocoa extract - which increases endorphins [beta-endorphin[23].
  3. Syrian Rue [24]: Syrian Rue is able to amplify Kratom's effects by providing additional euphoria/mood-lift and energizing the body's Spiritual Zones.
  4. We can add things like Maca - to potentiate Cannabinoid-activity [25] - Maca also blocks the breakdown of endorphins & enkephalins; increasing the effects of Kratom and opioids.
  5. Cannibidiol (CBD Oil) [26] [27]: It increases beta-endorphin as well and increases Happiness and easy-goingness. 
  6. Turmeric (Curcumin[28]: Turmeric blocks endorphins "feel good chemicals" from being broken down and it allows you digest/absorb Kratom better [29].
WARNING: Never combine Kratom with strong sedatives; especially Meds/Drugs like Seroquel (quetiapine[30].

NOTE: This entire post was written on the basis of True Science - and I also coordinated with others (cousin is a Medical Doctor) - he helped me put this together and found some locked-away VIP articles.

...There are hidden secrets about Kratom [2019].
I wrote a Book about a novel strain of Kratom not yet available on the market.

 
*This secret strain of Kratom is currently being studied by Russian Scientists as it has the unusual quality of regenerating MU-opioid receptors causing a 150% increase in receptors for it and other opiates/opioids to bind to.


One last strategy to enhance Kratom's effects is to supplement with Egyptian Blue Lotus (Nelumbo Nucifera). 

Blue Lotus Extracts [31]; it is an herb that contains the Dopamine-agonist compound Apomorphine [32] as well as other chemicals that support dopamine-release [33] [34] - it affects opioid-receptors and maximizes them [35]. This allows it to make Kratom more effective [36] [37] [38].

Blue Lotus has an important history by Ancient Egyptians and was the Pharaoh's prized plant remedy and used frequently to boost his Energy Level & Charisma. It also is rumored to be the reason why the Egyptian Royalty - lived longer and maintained greater connections to "The Dragon" [leviathan].

...That is the 'Serpent' emblem on the Pharaoh's Crown [link].

It (blue lotus) is unique and has rare chemicals that NO other herb has or contains [39].

***SOURCES/REFERENCES***


KRATOM AND THE OPIOID CRISIS
Innov Clin Neurosci. 2018 Jun 1; 15(5-6): 11.
Published online May-Jun 2018.
PMID: 30013812

Endorphinergic modulation of neural reward systems indicated by behavioral changes.
Pharmacol Biochem Behav. 1984 Aug;21(2):259-66.

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