Pregnenolone is a powerful brain neurosteroid that enhances Memory [1], Focus/Attention [2], Motivation [3] [4], reduces Anxiety [5] and stimulates the production of other Steroid hormones; like Testosterone [6].
It is studied for its effects on neuronal plasticity [7] [8] and Brain Cell Growth/Regeneration [9].
Perhaps most importantly is the STUDY - that shows that Pregnenolone blocks out Negative Emotions by suppressing Fear, pessimism, hopelessness and this is done by modulating emotional regulation circuits.
Pregnenolone can actually be the CURE for Loneliness - according to this study.
It also proves useful in BiPolar Depression [10] and Schizophrenia [11]; two particularly severe Mental Illnesses.
MY EXPERIENCES WITH VITAMIN WORLD PREGNENOLONE
- I noticed a Sense of Clarity but also mild stimulation on the FIRST-DAY of taking this product. It was unlike Caffeine - unlike ANY other supplement. It was like a subtle sense of motivation was there - like a small energy burning inside me...then - all of a Sudden my attention to my Environment is increased - and my thoughts became more Clear.
- I noticed increased Analytical-functions - that I analyze & dissect aspects of things - breaking them down into simpler points - and I found it easier to EXPLAIN such things to people - say At The Gym or in E-Mail responses.
- I noticed improved Reflexes, if something dropped, I would catch it...fast!
- I noticed MILDLY improved Libido after the Third Day.
- I noticed I had an enhanced ability to ascertain information & Instincts.
:::PREGNENOLONE PHARMACOLOGY:::
- Pregnenolone increases NMDA-activity [12] [13] which plays a Role in Learning & Memory [14] as well as Emotional Regulation [15].
- Pregnenolone acts as a Negative Allosteric Modulator of the CB1/CB2 - Cannibinoid-Receptors ("marijuana sites") [16].
- Pregnenolone also BLOCKS GABA-A receptors, especially in the presence of a Benzo drug [17] (benzodiazepine) like Xanax (alprazolam) or Klonopine (clonazepam).
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