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Friday, August 26, 2016

List of Natural / Herbal SSRI's : What are some Natural Serotonin-Reuptake Inhibitors?

Lots of articles exist talking about ''natural anti-depressants'' and 'natural serotonin boosters', however, most of them go into SAMe and other amino-based supplements, and the ones that DO talk about SSRI's are usually mixing them with other non SSRI supplements so it's difficult to filter which parts of the list are actually accurate.

Here is an effective 'master-list' of natural selective serotonin-reuptake inhibitors (NSSRI's/SSRI's). These supplements should not be used without a Physician's advice and they should not be used to treat, diagnose or cure any disease.

1.) Kanna : Is the most potent and proven of the natural SSRI's [1].  It also inhibits PDE-4 so this can lead to rolipram-like effects and amplify the antidepressant effect [2] [3]. It can be bought at TopExtracts here.
2.) St. John's Wort :  A well-known herbal anti-depressant which inhibits serotonin transporters and modulates brain levels of catecholamines [4] [5]. St.John's Wort may also calm excessive levels of norepinephrine by blocking dopamine conversion to norepinephrine [6] (in other words, it can help reduce the transformation of dopamine into norepinphrine and adrenaline). It can be bought at a good price @Amazon.
3.) Bacopa Monnieri Extract : A well-known and often used herbal memory booster, it has multiple pharmacological actions however its effects on mood are based on serotonin transporter (SERT) inhibition & expression modulation [7] [8] [9]. Buy it at Amazon here.


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