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Monday, June 25, 2018

Natural Opioid Receptor Agonists 2018 (Herbal Opiate Receptor Activators 2018)

Its well known that Opiates are of the strongest painkillers, and most pleasurable. They have humongous addiction potential [1] and often, horrible (even deadly!) withdrawal symptoms to go along with it [2]. This has created an "Opiate Epidemic" [3] and several 'mini-epidemics' before they were so mainstream [4]. They have continued to be sold under various street names and covers [5] and they have been the subject of sophisticated plots involving foreign Crime Lords [6].

...To deter some of the epidemic and to make Life easier for those who can't get Opiate painkillers - many have indulged in an herb called "Kratom" - which happens to be much safer than classical opiates and has less (overall) potential for addiction [7]. That is - that the potential for Kratom addiction is so low that it is negligible...as long as its not abused in excess over-the-top doses.

Other "herbal opiates" include Salvia Divinorum (which like Kratom can be smoked or made as a tea). Salvia is also known as "Diviner's Sage" - a Sage's or Spiritual Magicians favorite herb - therein lies the downside of using that particular herb for Pain...hallucinations are a common and often Desired side-effect. That is...because that herb is used for Rituals, but I made it known as it does have potent opioid-properties [8] - however, those properties hit a different type of Receptor called the "Kappa" or "K" opioid-receptor.

That receptor is known as a "Dysphoric" receptor - since it causes a decrease in Pleasure and Emotions - ironically, Salvia usually causes the opposite [9] which may be due to other properties, like Pro-Dopamine (D2-Partial Agonists) properties of the herb [10].

Lastly, only Kratom and CBD Oil have been proven as Natural Herbs (besides Marijuana) that can effectively and nearly immediately relieve Pain [11].

Although I don't believe any "herb" is inactive or useless, necessarily, I can say that many "Pain-Relieving" herbal formulas are merely snake oil.


...Produced and sold by Charlatan's and idiots.


Therefore - as opposed to our Normal Routine of listing Five or More Herbs - we are only listing TWO - those two just mentioned...but we will go over the Pharmacology of those herbs/natural ingredients.



THE VITAL TWO PAIN RELIEF HERBS WITH OPIATE PROPERTIES

Kratom (Mitragyna Speciosa): The King of all Pain Relieving herbs, has remarkable opiate-receptor agonist properties (U-opioid mainly) [12] and also has other dopamine-releasing properties [13] which can give a sense of pleasure while on the herb. Some strains are somewhat relaxing (Bali Kratom/Red Vein Riau). The most "stimulating" or Upper-type Kratom Strains are (Maenga Da & Red Borneo).

CBD Oil: Although 'technically' is an opioid-receptor antagonist/negative allosteric modulator [14] it also can enhance the natural production of beta-endorphin and enkephalin and can eventually upregulate the Opioid-activity very shortly [15]. Besides, it has enough "other properties" - regulating a number of different systems to relieve Pain and may modulate the 'hot-pepper' pathway (TRPV1) as well [16]. This pathway also interacts with endogenous opioids [17] and thus CBD may be called the "Master-Regulating" herb for Pain-Relief...and can *CERTAINLY* go along with Kratom in severe cases of Pain and - where EXTRA Euphoria is needed without withdrawal symptoms. ;-)
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Miscellaneous/Random Information: TRPV1 is supposedly involved in behavior and the irony is that Capsaicin and other hot pepper based pain-relief creams activate this pathway - perhaps making people "Hot-Headed"...for what its worth, maybe one could say that the study is in indicator for NOT USING Capsaicin-Creams Period...although, that may be a little extreme because it does help with minor pain - but many people can't handle the STING  and the BURN

...and it does cause Anxiety for some people during this process AKA the "Irritation Gone to The Brain" response!!!

STING CHAMELEON (MEGA MAN X) 2018 
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FLAME MAMMOTH (MEGA MAN X) 2018
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In/Tags: natural opioid receptor agonists, natural u opioid agonist, natural mu opioid agonist, herbal opiate agonist, herbal opiate 2018, natural opioid agonists 2018, natural opiate for sale 2018

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