"Serotonin 5-HT7-receptor blockers/antagonists may be one of the most ideal serotonergic modulating candidates with a distinct ability to decrease anxiety, and depressive symptoms, naturally(!)!"
There's one major plant compound/herb that can actually antagonize or block the 5-HT7 serotonin receptor, this would result in naturally lowering cyclic AMP and cortisol levels...
The herb is none other than the well-known SKULLCAP, infamous for reducing anxiety stronger than most other herbs! It's high efficacy and consistent results across a broad variability of patients with different backgrounds, shows that serotonin modulation is ideal for anxiety and depressive disorders...however, there's not many compounds available that can block specifically the 5-ht7 receptor without affecting others.
My recommended skullcap extract is below.
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