Mechanisms of Cannabis/Marijuana-Induced Sexual Dysfunction (Why does Pot/Marijuana Cause E.D)

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First off, I'd like to point out that I am NOT against Marijuana use - nor do I believe it should necessarily be classed into a group of 'dangerous chemicals'. I think that societal-moral integrity should include legalization of the plant. However, responsible use is always important - as with anything.

With that being said, I do NOT buy into Cannabis being a 'Panacea' (cure-all)...not only because the main method of administration is SMOKING it - but because simply, there is no such thing as a 'Panacea'. I've said on different occasions that the reason why there is no such thing as a panacea; is because of individuality. One person's Yang is another person's Yin - and for that reason alone the concept of one substance; drug , herb or otherwise , curing everything in everybody - is absolutely ridiculous!

Moving on.

Marijuana has many benefits; including against Pain and has beneficial effects on mood, cholesterol, and perhaps sociability in some instances. It obviously is more than effective as an appetite stimulant (e.g munchies induction) - but it's effects on sexual function; in men especially, are generally not so helpful. Even detrimental. 

There is the paradox of course where marijuana may 'relax' someone enough to FEEL as though their libido/sex drive has been increased - and the euphoria may also create or relay the perception of enhanced sexual interest in sensitive individuals - but from a vascular, and core neural perspective - Marijuana has generally detrimental effects on the process of arousal and erection in men. 

                                            THE HARD SCIENCE

Two particular mode's of action disturb male sexual function in regards to Marijuana. 

• The CB1 receptors become activated by THC (the psychoactive chemical responsible for most of 'ol Mary Jane's effects) = this leads to reductions in the second messenger cAMP; cyclic Adenosine monoPhosphate; which is a critical second messenger in both testosterone production and vasorelaxation. In simpler terms - THC/Marijuana reduce the levels of important chemicals that are needed to produce male sex hormones and to provide erectile support.  (1) (2) (3) (4) (5)
• The Activation of that same receptor class also leads to complex psychosomatic reactions - some of which may include paradoxical anxiety and increases of blood pressure - then leading to difficulty in getting or maintaining an erection . (6) (7)   Psychological ramifications ; such as the development of Psychotic symptoms during Marijuana use - may also play a role in adverse sexual events. 

Finally, impaired motor skills and in those who become 'too calm' on the Green - this in itself can negatively impact sexual functions, not just in men, but in women as well...after all - look at what Alcohol does!

                **REINFORCING THE MATTERS**

( OTHER CITATIONS / REFERENCES )

 Pot Use May Mellow Out Men's Sexual Function (LIVESCIENCE; by(Stephanie Pappas)

Is Smoking Weed Good or Bad for Erectile Dysfunction?
Written by Kimberly Holland | Published on June 25, 2015
Medically Reviewed by The Healthline Medical Team on June 25, 2015 { HEALTH LINE }

Marijuana and Erectile Dysfunction : Sex Health Matter :-: The website of the Sexual Medicine Society of North America, Inc.