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Tuesday, July 24, 2018

Mental (Psychological) & Other Methods to Enhance Euphoria from Stimulants (How to Enhance Stimulant Euphoria Reverse Stimulant Tolerance Supplements 2018)

This is another article following up on our collection of "Psychological Tactics" articles, which are taken from CIA-Based Concepts.




***Tempo-Management***

Tempo-Management is a method of more or less enhancing the stimulation of the CNS by performing certain actions in conjunction with utilizing 'Energy Sources' from the Environment.

...That is, the influence of ElectroMagnetic Influences and regulating the TYPE rather than the amount you are exposed to.

This can come with the help of Devices That Temporarily Stimulate Brain Wave activity. Thus over-riding a central step in the Process and with things like Music and Soundwaves + Physical actions like Push-Ups and even something as simple as "Aggressively" tapping ones feet.

You have to have an "intent" to do so.

That is - you must assert your Authority over your own Mind by utterly believing in and focusing on (channeling) your Mental Energy into the Process of Self-Amplification.

  • Doing Interval-Hypoxia, meaning do a FULL SET of 100-Pushups, FULL Pushups and hold your Breath completely during the last 30-40.
  • Use PLENTY of Aggression during Push-Ups and DON'T Listen to HARD-banger Music unless your CNS is SUPER Depressed. 
  • What you want is sort-of background, Transient-Consistent ENIGMATIC Music Beats; like this One!
  • Why that one? Because it isn't TOO HYPED or too CALM - but creates consistent Energy.
  • You should KNOW your Genetic Capacity.
  • That is - you can take an Ancestry test on AncestryDNA.com or 23andme.com.
  • ...Then upload the results on Promethease. Pay 5$ to get the Document uploaded and parsed for DNA-information.
  • Information on SNP's (Single-Nucleotide-Polymorphisms) can be used to determine your propensity towards certain neural-states or the lack thereof.
  • For example; there are genes that affect Glucose and the transport thereof, primarily on the Mitochondrial DNA (mtDNA) which is generally Maternal DNA - and these can affect propensity to Violence and Stimulant Threshold.
  • Regardless of ANY other factor - they are seen as "SUPERSEDING" factor.


***POTENTIATION BY UNDERSTANDING***

When you understand something fully - ANY Concept but ESPECIALLY about Pharmacology / NeuroScience - you know there are some things you just DON'T DO. So, for example, you don't COMBINE MAO-Inhibitors with STRONG Stimulants. Why? Because even if they are "selective" like Rasagiline - they still can lead to negative effects. Why? Because though Rasagiline and Dopamine have minimal effects on Blood Pressure themselves, the Rasagiline-induced PEA Release + Cocaine or Amphetamine induced PEA-release would likely overwhelm the CALCIUM-system and lead to increases in Blood Pressure REGARDLESS of if Coke or Amp NEVER raised it before. 

...Sometimes its not so simple as "adrenaline high" or "adrenaline low" - sometimes its the actual CHANNEL-Activity of the Nervous System which is generally more important than neurotransmitter levels (even though there is interaction!). 

Also, Endogenous Opiate-activity is a BIG factor in Stimulant-response.

Remember that Dopamine itself does NOT Produce Euphoria - ONLY through its interactions with the Endorphin-Enkephalin-system is the reason it does this [1] [2] [3].

Thus - optimizing the Endorphin-Enkephalin-system is the ONLY true way to increase Euphoria with stimulants. 

Note that 'Euphoria' is the only aspect truly related to CORE Opioid-pathways. 

Motivation is related to them through other interactions, less linear.

TOLERANCE TO STIMULANTS - WHAT GIVES?

If using stimulants "therapeutically" - there is no CONSISTENT Euphoria - it might happen for the first couple times - and there after *SLIGHTLY* but generally ONLY the SHARP Mental Clarity and alleviation of Procrastination and negative thinking occur.

...Even these effects dwindle a SLIGHT bit.

Eventually.

However, even though the "TOLERANCE" and Insensitivity aspects are pretty ANNOYING (I speak from Experience!) - you can do things about it!

1.) Only take them a few days a week and NOT at excessive doses.
2.) Take Inositol [1] and Forskolin [2] to increase/restore Dopamine D2-Receptors.
3.) Take Sulbutiamine to increase Dopamine D1-Receptors [3].
Many Redditor's noticed "insane motivation" restored after Sulbutiamine-use [4] - which translated to FULLY restored sensitivity to Amphetamines [5].
4.) Enhance "precursor" delivery to the Brains Dopamine-Neuron Terminals - that is - take SUBLINGUAL Caffeine + L-Tyrosine for optimum absorption - Ceretropic's Caffeine + NALT does just that and you hold the liquid UNDER your tongue and it absorbs through the mucus membranes causing effects WITHIN MINUTES!!!
5.) Take ZINC; in CREDIBLE ADHD-studies (on HUMANS) - Zinc "reduced the minimal effective dose of Amphetamine" [6].




***FUTURE MECHANISMS***

There is an "anti-depressant" in development which should (theoretically) at LOW-DOSES - potentiate STIMULANTS while reversing their negative side-effects like Low-Energy on Crash and Dependence [7] - its called CERC-501; it is a SELECTIVE Kappa-Opioid-Receptor Antagonist - which would then "disinhibit" Dopamine and possibly PREVENT Amphetamine-Psychosis as most Amphetamine-Psychosis is seen to be a KAPPA-OPIOID-Related effect [8].

...In any cases, HIGH-DOSES of the Drug would block mU (or "U") Opioid-receptors which would block Amphetamines pleasurable effects [19].



Sodium (NA) Channels - A "NEUROTOXIN" Called Aconitine May Over-Ride Everything...

  1. Aconitine - a chemical which I have limited stock of (just kidding!/maybe) - is a chemical with a "unique" Sodium-Channel Activating properties [9] - it produces acute (sudden) stimulation of the nervous system and bypasses all other levels of stimulation - directly doing something no other Drug on Earth is capable of Doing!
  2. Problem is - even MICRO quantities of Aconitine are TOXIC to the Brain/Body/Heart [10] - and thus - in order to achieve SYNERGY with Amphetamine - you'd have to calculate an EVEN TINIER dose than a "Safety" dose translated from Mouse --> Equivalency.
  3. Additionally - continued use may *potentially* lead to Heart Failure due to its "stressing" and Positive Inotropic Effect on the Heart [11].
  4. That being said - Military Scientists are exploring Medicinal Uses of Aconitine as well as novel methods of DEFENDING against its offensive (volatile) use.
  5. The Military by-and-large is interested in Artificially Enhanced Soliders after all [12].
  6. Aconitine - may though - have another use - development of similar compounds with SIMILAR (but not exact) properties - that can harness Sodium-Channel activation in discrete regions of the Brain without having Peripheral (bodily) effects [13].
...Problem is this will likely take AT LEAST 2-3 years to develop, another 1.5 years to Perfect and several years after that to get APPROVED - assuming it does...get approved.

Neurotoxicology is another great Read and dives into many other aspects of "neurotoxins" and potential medicinal uses.

BRAIN-NEUROGENIC DRUGS

DARPA's "Class-A" Brain-Building, Cognition Optimizing and Memory Maximizing Drug which was then "transferred" in ownership to a Private Company (probably to avoid scrutiny) - named NeuralStem - the Drug called "NSI-189" - which hit top pages and Hit Counts on the Immortalist/Transhumanist forum "LongeCity" - important partners of ours in the movement BTW. Its a game-changer.

It REBUILDS Lost/Damaged Synapses and REGENERATES & MAXIMIZES the HIPPOCAMPUS volume/cells [14].

Thus - NSI-189 is the most DIRECT Method of ABSOLUTELY Ensuring Amphetamines effects CONTINUE Unhindered in their MOUTH-WATERING EUPHORIA and self-Enchanted RAZOR-SHARP Blood-Drenching Focus.

Why? See Study Here.

Also - NSI-189 *principally* alleviates Anhedonia in relation to stimulant use/abuse [15] and WHO on this Great Earth would ever want to experience a loss-of-feelings and Pleasure??? (that is the DEFINITION of Anhedonia btw)

Not me...

But I think at some point - we all have. Persistent Anhedonia would be TERRIBLE!

Other Information: LongeCity's Publicly Stated goal is to "to conquer the blight of involuntary death". 

We (Area-1255) - aim for much higher - and more directly - to achieve Immortality and all of the Secrets of Human Enhancement; permanently advancing a New-Age of Human Civilization - full of Health, Vibrance and Creative Geniuses like myself - EVERYWHERE.

SELEGILINE/RASAGILINE AND OTHER MAO-B INHIBITORS
The Neuroprotective Dopaminergic Agents that Enhance ALL Stimulants.

Even though we don't necessarily recommend this Pathway - as seen above - we are exploring in further detail the concept of it for theoretical purposes anyhow.

While Selegiline (Deprenyl) has been known (and treasured) for Years in the Nootropics Community [!] - its role as a "stimulant enhancer" has shown both Good, and Ugly sides of this cocktail. The Good is that (hypothetically) the Selegiline may have "neuroprotective" effects that can stop/reverse Damage done by Methamphetamine or Cocaine - or others with similar effects (LSC,Ecstasy etc)

It would also enhance the effects itself of all Stimulants. That is because of the Synergy of preventing the breakdown of Dopamine released by Stimulants. 

Then many of them either 1.) Reduces synaptic clearance of the Dopamine or 2.) Having other direct actions on say, messenger system that affect neurotransmitter "firing" rates. 

...By this Logic it should be a PERFECT Cocktail. But...things on Paper don't always translate that way in practical Human Usage.

With that being said, a Selegiline - stack probably is advisable thus Rasagiline (Azilect) would be the way to go.

...However, Rasagiline is quite a bit more expensive, even on TOR/Black Market websites.

The idea - is that, Rasagiline is a focus-booster and a useful Anti-Aging drug that has less negative effects - i.e Methamphetamine Conversion by metabolites - and therefore, may spike Blood Pressure or cause Unpredictable Changes in Heart Rate or autonomic status.

Rasagiline's anti-aging properties are being explored in regards to Dementia [1] and Alzheimer's Disease [2] and Brain Research [3] and as well playing a role in boosting antioxidant status in The Brain [4] - and it can also increase short-term Memory in general - and has been a recent emergence on the LongeCity Community - in favor against Selegiline [5].

Rasagiline and Selegiline are both "anti-aging" drugs with substantial Life Extension properties - and they have shown remarkable Nootropic Properties in repeated studies [6] and can Reverse some Brain Damage caused by Toxins and in some cases Amphetamine exposure [7].

Finally, Rasagiline and Selegiline - are considered to be "Enhancement" Drugs to enhance Growth Hormone and Muscle Mass and improves Vitality and Energy, especially in Consideration of what they may do in combination of L-Dopa [8] or Dopamine Agonists [9].

Rasagiline - is a game-changer in treatment of Neurodegenerative Disorders such as Parkinson's Disease [10]. Rasagiline's actions in Parkinson's disease have been labeled as Neuroprotective [10], Symptom Alleviating [11], improving Cognition [12]

In addition Rasagiline has been demonstrated to reduce Negative Symptoms of Schizophrenia [13] and also it can improve Cognitive Functions in other Psychotic States; such as Amphetamine-induced Psychosis [14].

Anxiety - even though Selegiline and Selegiline withdrawal can provoke Anxiety. It is dose-dependent and Person-Dependent. Some people get ZERO-Anxiety, some have their Anxiety CURED from Selegiline. ESPECIALLY Social Anxiety. 








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In/Tags: mental methods to enhance euphoria, mental methods to enhance euphoria stimulants, mental to methods to enhance stimulants, psychological method to enhance stimulants, psychological technique increase cns 2018.

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